Monday, November 7, 2011

Therapeutic uses for hallucinogens? from the Physics Forum

This thread had one respondent aVibration that collated many cannaboid uses for neuroprotection and neurogenesis.
The complete forum here:
http://www.physicsforums.com/showthread.php?s=ffbf66d62a250bbab912cf4bc387b268&p=3595684#post3595684
The copy of aVibration here:
Marijuana is considered a hallucinogen by many governments around the world. It doesn't seem to have gotten much attention in this thread.

Followed are some links that were compiled by the National Organization for the Reform of Marijuana Laws (NORML) and found easily on their website, but the rules of this thread prohibit from linking to the page compiling these studies for future reference. I do not take credit for finding these studies or compiling them. (I omitted "Non-acute (residual) neurocognitive effects of cannabis use: A meta-analytic study. Journal of the International Neuropsychological Society. 2003" because one needed an authorization to follow the link provided.)

Cannabinoids & Neurogenesis


Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic and depressant-like effects. The Journal of Clinical Investigation. 2005
http://www.jci.org/articles/view/25509/version/1

Cannabis & Neuroprotection

Comparison of cannabidiol, antioxidants and diuretics in reversing binge ethanol-induced neurotoxicity. Journal of Pharmacology and Experimental Therapeutics. 2005
http://jpet.aspetjournals.org/conten...urcetype=HWCIT

Cannabidiol prevents cerebral infarction. Stroke. 2005
http://stroke.ahajournals.org/conten.../1071.abstract

Post-ischemic treatment with cannabidiol prevents electroencephalographic flattening, hyperlocomotion and neuronal injury in gerbils. Neuroscience Letters. 2003
http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Citation

Neuroprotection by Delta9-tetrahydrocannabinol, the main active compound in marijuana, against ouabain-induced in vivo excitotoxicity. Journal of Neuroscience. 2001
http://www.jneurosci.org/content/21/17/6475.full

Cannabidiol and Delta9-tetrahydrocannabinol are neuroprotective antioxidants. Proceedings of the National Academy of Sciences. 1998
http://www.pnas.org/content/95/14/8268.full

Cannabinoids & Glioma

Cannabinoids selectively inhibit proliferation and induce cell death of cultured human glioblastoma multiforme cells. Journal of Neurooncology. 2005
http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Citation

Cannabinoids and cancer. Mini-Reviews in Medicinal Chemistry. 2005
http://www.benthamscience.com/mrmc/c...mrmc5-10.htm#6

Anti-tumor effects of cannabidiol, a non-psychotropic cannabinoid, on human glioma cell lines. Journal of Pharmacology and Experimental Therapeutics. 2003
http://jpet.aspetjournals.org/content/308/3/838.full

Cannabinoids & Neurodegeneration

Cannabinoids and neuroprotection in CNS inflammatory disease. Journal of the Neurological Sciences. 2005.
http://www.sciencedirect.com/science...22510X05000778

Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 2004
http://www.letfreedomgrow.com/cmu/am..._sclerosis.htm

Cannabinoids inhibit neurodegeneration in models of multiple sclerosis. Brain. 2003
http://brain.oxfordjournals.org/cont...6/10/2191.full


Cannabis & Cognition


Lack of hippocampal volume change in long-term heavy cannabis users. American Journal of Addictions. 2005
http://marijuana.researchtoday.net/archive/2/4/358.htm

Neuropsychological consequences of regular marijuana use: a twin study. Psychological Medicine. 2004
http://journals.cambridge.org/action...ine&aid=255433

Current and former marijuana use: preliminary findings of a longitudinal study of effects on IQ in young adults. Canadian Medical Association Journal. 2002
http://www.cmaj.ca/content/166/7/887.abstract

Neuropsychological Performance in Long-term Cannabis Users. Archives of General Psychiatry. 2001
http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Abstract

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