Neuroprotection by Aspirin and Sodium Salicylate Through Blockade of NF-κB Activation

Just think, regular aspirin can be used against the neuronal cascade of death. And my doctor only had 10 years to be able to incorporate this into hyperacute therapy. Written in 1996. I don't care if it was only tested in rats.
http://www.sciencemag.org/content/274/5291/1383.short
Aspirin (acetylsalicylic acid) is a commonly prescribed drug with a wide pharmacological spectrum. At concentrations compatible with amounts in plasma during chronic anti-inflammatory therapy, acetylsalicylic acid and its metabolite sodium salicylate were found to be protective against neurotoxicity elicited by the excitatory amino acid glutamate in rat primary neuronal cultures and hippocampal slices. The site of action of the drugs appeared to be downstream of glutamate receptors and to involve specific inhibition of glutamate-mediated induction of nuclear factor kappa B. These results may contribute to the emerging theme of anti-inflammatory drugs and neurodegeneration.