You'll have to read this blogger at the url. Signalling to get migrating neurons to the correct place. Hey, we should be able to mimic this and get new neurons to the damaged areas. Tell your researcher about this. This could be really wonderful for all us chronic survivors.
http://www.guardian.co.uk/science/neurophilosophy/2012/feb/02/1
Star-shaped cells called astrocytes build blood vessel highways for migrating neurons.
The journey undertaken by newborn neurons in the adult mouse brain is like the cellular equivalent of the arduous upstream migration of salmon returning to their hatching river. Soon after being born in the subventricular zone near the back of the brain, these cells embark on a long-distance migration to the front-most tip of the brain. Their final destination – the olfactory bulb – is the furthest point from their birth place, and they travel two-thirds of the length of the brain to get there.
Several years ago, a team of researchers from Canada showed that the pathway for this migration – called the rostral migratory stream – is lined with a scaffold of capillaries, and that the young cells crawl along the blood vessels during their journey. In a follow-up study, they now report that the construction and organization of the blood vessel scaffold is orchestrated by star-shaped cells called astrocytes.
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