So I wonder if any testing has been done to see if nitroglycerin(glyceryl trinitrate) given to strokees opens the blood vessels that were constricted due to pericytes. Or is this one of those cases where the worry about creating a bleed causes everyone to not do anything.
http://stroke.ahajournals.org/content/20/12/1733.short
Its only 23 years old, Who followed up on this? We need a forensic specialist to see what has happened to all the research that showed promise but never made it to clinical practice.
We used a combination of transcranial Doppler ultrasonography and single-photon emission computed tomography to noninvasively assess changes in the diameter of the middle cerebral artery induced by sublingual ( 'under the tongue')nitroglycerin in 10 healthy subjects. Nitroglycerin reduced mean blood flow velocities without concurrently changing regional cerebral blood flow in the perfusion territory of this vessel. Our results strongly suggest that nitroglycerin causes vasodilatation(widening of blood vessels) of the basal intracranial arteries.
No comments:
Post a Comment