If only there was open access to scientific journals. I would take it on myself to solve the questions. Someone needs to translate this stuff into a therapy protocol or at least postulate a theory that can be tested.
http://www.frontiersin.org/Neurogenesis/10.3389/fnins.2012.00071/abstract
MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene
expression at the post-transcriptional level by mediating mRNA
degradation or translational inhibition. MiRNAs are implicated in many
biological functions, including neurogenesis. It has been shown that
miRNAs regulate multiple steps of neurogenesis, from neural stem cell
proliferation to neuronal differentiation and maturation. MiRNAs execute
their functions in a dynamic and context-dependent manner by targeting
diverse downstream target genes, from transcriptional factors to
epigenetic regulators. Identifying context-specific target genes is
instrumental for understanding the roles that miRNAs play in
neurogenesis. This review summarizes our current state of knowledge on
the dynamic roles that miRNAs play in neural stem cells and
neurogenesis.
Too bad you don't offer a reaction titled "Pompous A-hole" . I suspect that would be the overwhelming choice.
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