Not sure exactly how one would get these microparticles.
http://www.ncbi.nlm.nih.gov/pubmed/22621230
Abstract
Activated platelets shed
microparticles, which contain variety of growth factors central to
angiogenesis and neurogenesis. The aim of this study was to explore
whether platelet derived microparticles (PMP) can boost endogenous
neural stem cells dependent repair mechanisms following stroke in a rat
model. To examine the effects of PMP therapy in-vivo, we delivered
PMP or vehicle via a biodegradable polymer to the brain surface after
permanent middle cerebral artery occlusion (PMCAO) in rats. Rats
were tested with the neurological severity score and infarct volumes
were measured at 90 days post-ischemia. Immunohistochemistry was used
to determine the fate of newborn cells and to count blood vessels in
the ischemic brain. The results show that PMP led to a dose
dependent increase in cell proliferation, neurogenesis and angiogenesis
at the infarct boundary zone and significantly improved behavioral
deficits.
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