Monday, May 14, 2012

Unmasking the benefits of B vitamins in stroke prevention

Not much to go on here, can't tell if this is dietary or supplements. Your doctor should be subscribing to The Lancet. You can check out other commentary here:
http://oc1dean.blogspot.com/2011/12/jama-commentary-contends-vitamin.html
The Lancet here:
 http://www.thelancet.com/journals/laneur/article/PIIS1474-4422%2812%2970094-7/fulltext
 Vitamin B12 and folate are key mediators of homocysteine metabolism. Low plasma vitamin B12 and folate concentrations are associated with hyperhomocysteinaemia, with consequent premature atherosclerosis and increased risk of cardiovascular and cerebrovascular disease.1,2 In a meta-analysis of observational studies, a 25% reduction in homocysteine concentrations (roughly 3 μmol/L [0·41 mg/L]) corresponded with an 11% lower risk of ischaemic heart disease and a 19% lower risk of stroke.3 The Heart Outcomes Prevention Evaluation 2 (HOPE 2) trial4 and re-analysis of data from the Vitamin Intervention for Stroke Prevention (VISP) study5 (both trials in which patients received high doses of B vitamins) have confirmed these findings for stroke.

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