Tuesday, September 25, 2012

Success Seen for tPA in Carotid Artery Stroke

I'm sure someone medical can explain this to me. But how do you have a stroke when a carotid artery is blocked and you have a functioning Circle of Willis? My carotid is totally blocked and I did not have a stroke whenever it closed up 4 years ago.

Success Seen for tPA in Carotid Artery Stroke


Intravenous thrombolysis should be considered a preferred first-line treatment for acute occlusion of the cervical internal carotid artery (ICA), a small retrospective study suggested.
Among 13 patients treated with recombinant tissue plasminogen activator (rtPA) within the recommended treatment window, seven had good functional recovery at 3 months, compared with only one of eight given primary endovascular treatment, according to Raymond C.S. Seet, MD, of the National University of Singapore, and colleagues.
Predictors of favorable functional outcome in patients treated with rtPA included good collateral distal blood flow, with an odds ratio of 20 (95% CI 2 to 242, P=0.02) and neurologic recovery within 24 hours, with an odds ratio of 77 (95% CI 3 to 500, P=0.02), the researchers reported online in Archives of Neurology.

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