Tuesday, February 26, 2013

Long Course Hyperbaric Oxygen Stimulates Neurogenesis and Attenuates Inflammation after Ischemic Stroke

Your doctor will need to decipher this and see if the conclusions match the results. I doubt it.
http://scholar.google.com/scholar_url?hl=en&q=http://downloads.hindawi.com/journals/mi/2013/512978.pdf&sa=X&scisig=AAGBfm2LTyPWIJ_t-r0f2O6-52_ql2KWfg&oi=scholaralrt
Several studies have provided evidence with regard to the neuroprotection benefits of hyperbaric oxygen (HBO) therapy in cases
of stroke, and HBO also promotes bone marrow stem cells (BMSCs) proliferation and mobilization. This study investigates the
influence of HBO therapy on the migration of BMSCs, neurogenesis, gliosis, and inflammation after stroke. Rats that sustained
transient middle cerebral artery occlusion (MCAO) were treated with HBO three weeks or two days. The results were examined
using a behavior test (modified neurological severity score, mNSS) and immunostaining to evaluate the effects of HBO therapy
on migration of BMSCs, neurogenesis, and gliosis, and expression of neurotrophic factors was also evaluated. There was a lower
mNSS score in the three-week HBO group when compared with the two-day HBO group. Mobilization of BMSCs to an ischemic
area wasmore improved in long course HBO treatments, suggesting the duration of therapy is crucial for promoting the homing of
BMSCs to ischemic brain by HBO therapies. HBO also can stimulate expression of trophic factors and improve neurogenesis and
gliosis. These effects may help in neuronal repair after ischemic stroke, and increasing the course of HBO therapy might enhance
therapeutic effects on ischemic stroke.

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