Friday, May 17, 2013

Corticospinal responses of quadriceps are abnormally coupled with hip adductors in chronic stroke survivors

So ask your therapist what therapy protocol will correct that problem. You do expect them to know how to fix it, don't you? Sounds right up your alley Amy. And I know I'm being a bastard. I expect a lot from myself and even more from my medical team.
http://search.naric.com/research/rehab/redesign_record.cfm?search=2&type=all&criteria=J65578&phrase=no&rec=120874

NARIC Accession Number: J65578.  What's this?
ISSN: 0014-4886.
Author(s): Krishnan, Chandramouli; Dhaher, Yasin.
Project Number: H133E070013.
Publication Year: 2012.
Number of Pages: 8.
Abstract: Study investigated whether the neural substrates mediating abnormal activation patterns after stroke are of cortical origin. Eight chronic stroke survivors, seven able-bodied young control subjects and four older adults participated in this research study. Data from older adults were used to evaluate whether aging contributes to abnormal coupling of the corticospinal responses. A novel transcranialmagnetic stimulation (TMS) protocol was developed to evaluate the extent of abnormal across-joint coupling of corticospinal responses in chronic stroke survivors. It was hypothesized that the stroke subjects would demonstrate abnormal higher corticospinal responses of the quadriceps muscle group during an isometric hip adduction task. TMS-elicited motor evoked potentials (MEPs) were recorded from the paretic leg of the stroke survivors and from the dominant leg of the control subjects using surface electromyography. Results indicated that, in stroke survivors, the magnitudes of MEPs of the vastus lateralis and vastus medialis during isometric hip adduction were significantly higher than those recorded during knee extension at similar background activity. Furthermore, MEP coupling ratios of the quadriceps muscles were significantly different than those observed in healthy controls. No significant differences in MEP coupling ratios were observed between the younger and older adults. These findings provide evidence for the first time that stroke subjects exhibit abnormal excitability of the quadricepsmuscle corticospinal neurons when performing isometric hip adduction. Importantly, the abnormal corticospinal responses observed in stroke subjects were not mediated by aging.

1 comment:

  1. You should expect a lot, I certainly do. I'm a horrible bitch to most of my medical team.

    ReplyDelete