Wednesday, October 2, 2013

Brain reorganization after endovascular treatment in a patient with a large arteriovenous malformation: the role of diagnostic and functional neuroimaging techniques


No clue what this means, that is what your non functional doctor is for.
http://www.ncbi.nlm.nih.gov/pubmed/24070082

Source

Department of Neuroradiology, Montreal Neurological Institute and Hospital, McGill University; Montreal, Canada - E-mail: donatella.tampieri@mcgill.ca.

Abstract

We describe a case of brain cortical reorganization after embolization of a large right temporal arteriovenous malformation. A comprehensive imaging protocol, including functional magnetic resonance imaging (fMRI), cortical thickness analysis and 320-row computed tomography (CT) perfusion was used to provide information on brain plasticity and potential steal phenomenon. A 25-year-old man known for a right temporal grade V Spetzler-Martin classification arteriovenous malformation (AVM) presented with left progressive hemiparesis. He underwent functional 3T magnetic resonance imaging (fMRI), cortical thickness analysis, and CT perfusion (CT 320 row, Aquilion ONE, Toshiba, Tokyo, Japan) before and after endovascular treatment.

The results were compared to look for modifications in brain perfusion and organization. An improvement in the left hemiparesis and a reorganization of motor function were observed after endovascular treatment. Modifications in the angioarchitecture and perfusion of an extensive AVM may be accompanied by a functional and structural reorganization of the brain. The location in the so-called eloquent regions may not be sufficient to explain the wide spectrum of symptoms that these patients can present. A more comprehensive approach considering a global involvement of the brain in patients with large AVMs is suggested to achieve the best treatment strategy and to stage treatment in incurable AVMs.

1 comment:

  1. This one is like mine. Large bleeding mass in an eloquent location...rendering "atypical" symptoms for location. That was part of the problem in getting any md to figure out my case. The symptoms didn't match the location....so much for brain mapping. My guess is that the mass effect was creating some of the symptoms.

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