Wake-Up to Wake-Up Stroke!

5-30% of patients come to the ER with a wake-up stroke. Because they don't know when it occurred, they can't get tPA. I can't tell if this editorial has an answer but my answer is simple. Use a smaller bolus and deliver it directly to the clot with magnetic nanoparticles.  With direct and smaller delivery the chance of bleeding should be reduced substantially. But since I have no medical training it's obvious that this is a stupid idea.

Wake-Up to Wake-Up Stroke!