Saturday, July 19, 2014

CURRENT AND EXPERIMENTAL TREATMENT OF STROKE

This table is interesting. Your doctor should be closely following these trials. Which ones is your doctor willing to use on your next stroke? None? Then your doctor is actively allowing millions of neurons to die. Too bad for you.
http://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=7&cad=rja&uact=8&ved=0CGoQFjAG&url=http%3A%2F%2Fwww.acnp.org%2Fasset.axd%3Fid%3D32d82c88-062e-4550-8508-34ed66512699&ei=6ajKU-jAN4_hsATAmYCgDw&usg=AFQjCNEgSITtfY2YbhtqlTL9MZZfDaumYg&sig2=Wk5jxIcIYVygPR1ktZphKA&bvm=bv.71198958,d.cWc
TABLE 93.1. CLINICAL TRIALS FOR ACUTE
STROKE TREATMENT a
Drugs to improve blood flow
    Antithrombotic
    Heparin
    Nadroparin (low molecular weight heparin)
    Tinzaparin (low molecular weight heparin)
    Danaparoid (low molecular weight heparinoid, Org 10172)
Anti-platelet
    Aspirin
    Abciximab
Fibrinogen depleting
    Ancrod
Improve capillary flow
    Pentoxifylline
Thrombolytics
     Pro-urokinase
     Tissue plasminogen activator
     Streptokinase
     Urokinase
Drugs to protect brain tissue (neuroprotective agents)
     Calcium channel blockers
     Nimodipine
     Flunarizine
Free radical scavengers—antioxidants
     Ebselen
     Tirilazad
     NPY-059
GABA agonists
     Clomethiazole
Glutamate antagonists
     AMPA antagonists
          GYKI 52466
          NBQX
          YM90K
          YM872
          ZK-200775 (MPQX)
     Kainate antagonist
          SYM 2081
     NMDA antagonists
          Competitive NMDA antagonists
              CGS 19755 (Selfotel)
          NMDA channel blockers
              Aptiganel (Cerestat)
              Dextrorphan
              Dextromethorphan
              Magnesium
                   Memantine
                   MK-801
                   NPS 1506
                   Remacemide
                   AR-R15896AR
                   HU-211
               Glycine site antagonists
                   ACEA 1021
                   GV150526
               Polyamine site antagonists
                   Eliprodil
                   Ifenprodil
           Growth factors
                Fibroblast Growth factor (bFGF)
           Leukocyte adhesion inhibitor
                Anti-ICAM antibody (Enlimomab)
                Hu23F2G
           Nitric oxide inhibitor
                 Lubeluzole
           Opioid antagonists
                 Naloxone
                 Nalmefene
            Phosphatidylcholine precursor
                 Citicoline (CDP-choline)
            Serotonin agonists
                 Bay × 3072
            Sodium channel blockers
                  Fosphenytoin
                  Lubeluzole
                  619C89
           Potassium channel opener
                  BMS-204352

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