Effects of nutrition on leucocyte infiltration and neurogenesis after stroke in aged rats

Probably another reason drugs that work in rodents don't always work in humans.
http://www.jni-journal.com/article/S0165-5728%2814%2900597-9/abstract

• Abstract
• Full Text

Aim: The role of inflammation in stroke lesion development is currently intensively investigated. Most experimental models make use of young animals with normal nutritional status despite the fact that ageing and obesity are important risk factors for patients to suffer from cerebrovascular disease. Both ageing and nutritional customs are known to alter inflammatory responses and to affect stroke outcome. However, no data are available on the effect of nutrition regimen on stroke outcome and brain inflammation in aged animals.