Glutamate Excitotoxicity and Neurodegeneration

Your doctor should be able to use this understanding to figure out if two of the processes involved in the neuronal cascade of death are the reason for your 33% dementia chance post-stroke from an Australian study?
What exactly is your doctor doing to stop those two neuronal death processes and maybe prevent your dementia?
http://scholar.google.com/scholar_url?url=http://omicsonline.com/open-access/glutamate-excitotoxicity-and-neurodegeneration-1747-0862-1000141.pdf&hl=en&sa=X&scisig=AAGBfm1cEQLfAP2l2iqHDqrC0PO2p08zoA&oi=scholaralrt
Ezza HSA1* and Khadrawyb YA2
1Zoology Department, Faculty of Science, Cairo University, Giza, Egypt
2Medical Physiology Department, Medical Division, National Research Center, Giza, Egypt
*Corresponding author: Ezza HSA, Zoology Department, Faculty of Science, Cairo University, Giza, Egypt, Tel: 20237753565; Fax: +202 33387758; E-mail:
hebasal@yahoo.com
Rec Date: May 20, 2014; Acc date: October 06, 2014; Pub date: October 08, 2014
Copyright: © 2014 Ezza HSA. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use,
distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract
Glutamate plays crucial roles in the physiology of the central nervous system as it can control many functions such as memory, learning, cognitive, emotional, endocrine and other visceral functions. In addition, glutamate is the major excitatory neurotransmitter in the mammalian central nervous system. It has the potential to be involved in the pathogenesis of many CNS diseases either due to excessive release, reduced uptake or alteration of receptor functions. Growing evidence links glutamate excitotoxicity to various neurodegenerative diseases as cerebral ischemia, epilepsy, Alzheimer's disease, Parkinsons' disease and multiple sclerosis. In addition, several
environmental pollutants result in excessive glutamatergic neurotransmission and may eventually lead to neurodegenerative diseases.