I'm betting 50 years before this is rolled out to stroke hospitals. Trillions of neurons will die as a result of that delay.
http://medicalxpress.com/news/2015-02-drug-treatment-survivors-outcomes.html
Promising results for a new drug treatment for ischaemic stroke patients have been published today in the journal Lancet Neurology.
A new drug treatment, Tenecteplase, has been shown to have similar outcomes in limiting the damage done in the brain after a stroke compared with current treatments. Crucially however, it is also far easier to administer and may also be safer.
Ischaemic strokes are caused by a blood clot blocking a blood vessel
in the brain, and are treated by injecting 'clot-busting' drugs that
dissolve the blood clot, restoring blood flow. There is a crucial four
and a half hour window after an ischaemic stroke in which giving
clot-busting drug treatment is effective in limiting damage and improving outcome.
Currently, only one drug – Alteplase – is used for acute treatment of
stroke. The study, led by Professor Keith Muir, SINAPSE Chair of
Clinical Imaging and Consultant Neurologist at the University of
Glasgow, compared Alteplase with a newer clot-busting drug called
Tenecteplase.
The study, funded by the Stroke Association, showed that incidences
of serious adverse events did not differ between the two groups and all
neurological and radiological outcomes were similar, despite by chance
there being slightly more very severe strokes in the Tenecteplase group.
The results also revealed that potentially fewer people had a brain
haemorrhage as a complication of treatment with Tenecteplase.
Researchers believe that, as Tenecteplase can be given more easily
than Alteplase, it could become a less expensive and easier to
administer treatment for ischaemic stroke patients; a larger clinical
trial will be needed in the to test Tenecteplase fully, and plans for
such a trial are at an advanced stage.
Professor Muir said: "Every minute is crucial in treating stroke and
we need better treatment options. Any treatment that is easier to
deliver and potentially safer could mean the difference between a good
recovery and someone suffering seriously debilitating long term effects.
"We are planning a larger scale trial to investigate these results further."
Dr Dale Webb, Director of Research and Information at the Stroke
Association, said: "The brain damage caused by a stroke can leave people
facing a devastating level of disability. Currently, our only tool to
treat ischaemic stroke, caused by a blockage of an artery in the brain,
is thrombolysis. This type of treatment benefits around one in seven
people treated. There is only one drug licensed for thrombolysis, which
is Alteplase.
"This important research investigating an alternative to Alteplase
could pave the way for an improvement in thrombolysis. A more effective
way to deliver clot-busting treatment to stroke patients could be life-changing; when stroke strikes, time saved is brain saved."
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