Adult hippocampal neurogenesis, aging and neurodegenerative diseases: Possible strategies to prevent cognitive impairment.

Does your doctor have ANY strategies to prevent and/or fix your cognitive decline post-stroke?
http://europepmc.org/abstract/med/26059358
Vivar C

Current Topics in Medicinal Chemistry [2015]

Type: Journal Article

Abstract

Highlight Terms Gene Ontology(1) Diseases(5) Species(3) Chemicals(3)

The adult brain of humans and other mammals continuously generates new neurons throughout life. However, this neurogenic capacity is limited to two brain areas, the dentate gyrus (DG) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricle. Although the DG generates new neurons, its neurogenic capacity declines with age and neurodegenerative diseases such as Alzheimer's disease (AD) and Huntington's disease (HD). This review focuses on the role of newly-born neurons in cognitive processes, and discusses some of the strategies proposed in humans and animals to enhance neurogenesis and counteract age-related cognitive deficits, such as physical exercise and intake of natural products like omega-3 fatty acids, curcumin andflavanols.