http://www.biomedcentral.com/1472-6882/15/318
- † Equal contributors
1
Department of Biomedical Engineering, National Cheng Kung University, 1
University Road, Tainan City 701, Taiwan
2 School of Chinese Medicine for Post-Baccalaureate, I-Shou University, 8 Yida Road, Kaohsiung City 824, Taiwan
3 Department of Surgery, China Medical University Hospital, Taichung, Taiwan
4 Department of Surgery, University of Illinois, Chicago, USA
5 Department of Chinese Medicine, E-DA Hospital, Kaohsiung, Taiwan
6 Department of Anesthesiology, Taipei Medical University Hospital, 252 Wuxing St., Taipei 110, Taiwan
7 Health Policy Research Center, Taipei Medical University Hospital, Taipei, Taiwan
8 School of Medicine, Taipei Medical University, Taipei, Taiwan
9 School of Chinese Medicine, China Medical University, 91 Hsueh-Shih Road, Taichung 404, Taiwan
2 School of Chinese Medicine for Post-Baccalaureate, I-Shou University, 8 Yida Road, Kaohsiung City 824, Taiwan
3 Department of Surgery, China Medical University Hospital, Taichung, Taiwan
4 Department of Surgery, University of Illinois, Chicago, USA
5 Department of Chinese Medicine, E-DA Hospital, Kaohsiung, Taiwan
6 Department of Anesthesiology, Taipei Medical University Hospital, 252 Wuxing St., Taipei 110, Taiwan
7 Health Policy Research Center, Taipei Medical University Hospital, Taipei, Taiwan
8 School of Medicine, Taipei Medical University, Taipei, Taiwan
9 School of Chinese Medicine, China Medical University, 91 Hsueh-Shih Road, Taichung 404, Taiwan
BMC Complementary and Alternative Medicine 2015, 15:318
doi:10.1186/s12906-015-0828-8
Sun-Fa Chuang, Chun-Chuan Shih, Tainsong Chen and Chien-Chang Liao contributed equally to this work.
The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1472-6882/15/318
Sun-Fa Chuang, Chun-Chuan Shih, Tainsong Chen and Chien-Chang Liao contributed equally to this work.
The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1472-6882/15/318
| Received: | 26 February 2015 |
| Accepted: | 25 August 2015 |
| Published: | 9 September 2015 |
© 2015 Chuang et al.
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Abstract
Background
Whether acupuncture protects stroke patients from acute myocardial infarction (AMI)
has not been studied previously. The purpose of this study was to investigate the
risk of AMI among stroke patients receiving acupuncture treatment.
Methods
Taiwan’s National Health Insurance Research Database was used to conduct a retrospective
cohort study of 23475 stroke patients aged 40–79 years receiving acupuncture treatment
and 46950 propensity score-matched stroke patients not receiving acupuncture treatment
who served as controls from 2000 to 2004. Both stroke cohorts were followed until
the end of 2009 and were adjusted for immortal time to measure the incidence and adjusted
hazard ratios (HRs) with 95 % confidence intervals (CIs) for new-onset AMI in multivariate
Cox proportional hazard models.
Results
Stroke patients who received acupuncture treatment (9.2 per 1000 person-years) exhibited
a lower incidence of AMI compared with those who did not receive acupuncture treatment
(10.8 per 1000 person-years), with an HR of 0.86 (95 % CI, 0.80–0.93) after adjusting
for age, sex, low income, coexisting medical conditions and medications. The relationship
between acupuncture treatment and AMI risk was investigated in female stroke patients
(HR, 0.85; 95 % CI, 0.76–0.95), male stroke patients (HR, 0.87; 95 % CI, 0.80–0.95),
patients from 50 to 59 years of age (HR, 0.75; 95 % CI, 0.63–0.90), patients from
60 to 69 years of age (HR, 0.85; 95 % CI, 0.75–0.95), patients suffering from ischemic
stroke (HR, 0.87; 95 % CI, 0.79–0.95), and patients suffering from hemorrhagic stroke
(HR, 0.62; 95 % CI, 0.44–0.88).
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