Monday, September 7, 2015

Newer devices reduce aspiration times, improve outcomes after stroke treatment

And once again these supposedly smart people do not discuss anything about solving the neuronal cascade of death.  Does no one have two functioning neurons to rub together?
http://www.healio.com/cardiology/intervention/news/online/%7B2a000be6-74c8-4c1d-874c-c61dae654e75%7D/newer-devices-reduce-aspiration-times-improve-outcomes-after-stroke-treatment?utm_source=maestro&utm_medium=email&utm_campaign=cardiology%20news

The use of newer, larger catheters for endovascular treatment of acute ischemic stroke was associated with shorter aspiration time and improved functional outcomes, according to data presented at the Society for NeuroInterventional Surgery Annual Meeting.
Researchers evaluated data on 932 patients (mean age, 66 years) with stroke who underwent endovascular treatment with the Penumbra Aspiration System (Penumbra Inc.). The patients were culled from six prospective and retrospective trials of the device.
“The aim … was to evaluate if there was a corresponding improvement in procedural times over the course of the evolution of these devices,” the researchers wrote in the abstract.
Outcomes of interest included clinical outcomes at 90 days, as indicated by modified Rankin scale, and aspiration time.
All patients received treatment within 8 hours of stroke onset. The mean time to presentation was 2.1 hours and the mean time to groin access was 4.4 hours. Upon admission, patients had a median NIH Stroke Scale score of 18 and a TIMI score of 0 to 1. The middle cerebral artery accounted for three-quarters of vessel locations.
After undergoing endovascular treatment, 84% of patients achieved revascularization to a TIMI score of 2 to 3.
Factors associated with shorter aspiration time included female sex, use of larger catheters, and timely presentation and treatment, according to univariable analysis. Shorter aspiration time was associated with improved outcomes (P = .0044). Younger patients, women, those with a lower baseline NIH Stroke Scale, shorter procedure times and revascularization to a TIMI score of 2 to 3 also were linked to improved outcomes.
Multivariable analysis adjusted for age, baseline NIH Stroke Scale and status after revascularization indicated an association between aspiration time and 90-day outcomes (P = .003), with a greater risk for poor outcome with increasing aspiration time.
“As each new generation of devices provides improved tools for our treatment arsenal, we are able to adjust our approach to maximize efficiencies and results for our patients,” Donald Frei, MD, president of the Society of NeuroInterventional Surgery and neurointerventionalist at Swedish Medical Center in Englewood, Colorado, said in a press release. “Thankfully, each generation … has proven to reduce procedure time, which raises the chance of a successful operation.” – by Adam Taliercio
Reference:
Frei D, et al. Implementation of new technological advances of endovascular treatment in acute ischemic stroke provides overall improvement in procedural times. Presented at: Society of NeuroInterventional Surgery Annual Meeting; July 27-30, 2015; San Francisco.

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