This would seem to be incredibly useful for those drugs delivered to the brain through the nasal cavity. But don't worry, This will never be followed
up since we have NO stroke leadership.
http://www.biosciencetechnology.com/news/2016/01/researchers-ride-new-sound-wave-health-discovery?
Acoustics experts have created a new class of sound wave - the first
in more than half a century - in a breakthrough they hope could lead to a
revolution in stem cell therapy.
The team at RMIT University in Melbourne, Australia, combined two
different types of acoustic sound waves called bulk waves and surface
waves to create a new hybrid: "surface reflected bulk waves".
The first new class of sound wave discovered in decades, the powerful
waves are gentle enough to use in biomedical devices to manipulate
highly fragile stem cells without causing damage or affecting their
integrity, opening new possibilities in stem cell treatment.
Dr Amgad Rezk, from RMIT's Micro/Nano Research Laboratory, said the
team was already using the discovery to dramatically improve the
efficiency of an innovative new "nebuliser" that could deliver vaccines
and other drugs directly to the lung.
"We have used the new sound waves to slash the time required for
inhaling vaccines through the nebuliser device, from 30 minutes to as
little as 30 seconds," Rezk said.
"But our work also opens up the possibility of using stem cells more
efficiently for treating lung disease, enabling us to nebulise stem
cells straight into a specific site within the lung to repair damaged
tissue.
"This is a real game changer for stem cell treatment in the lungs."
The researchers are using the "surface reflected bulk waves" in a
breakthrough device, dubbed HYDRA, which converts electricity passing
through a piezoelectric chip into mechanical vibration, or sound waves,
which in turn break liquid into a spray.
"It's basically 'yelling' at the liquid so it vibrates, breaking it down into vapour," Rezk said.
Bulk sound waves operate similar to a carpet being held at one end
and shaken, resulting in the whole substrate vibrating as one entity.
Surface sound waves on the other hand operate more like ocean waves
rolling above a swimmer's head.
"The combination of surface and bulk wave means they work in harmony
and produce a much more powerful wave," said Rezk, who co-authored the
study with Ph.D. researcher James Tan.
"As a result, instead of administering or nebulising medicine at
around 0.2ml per minute, we did up to 5ml per minute. That's a huge
difference."
The breakthrough HYDRA device is improving the effectiveness of a
revolutionary new type of nebuliser developed at RMIT called Respite.
Cheap, lightweight and portable, the advanced Respite nebuliser can
deliver everything from precise drug doses to patients with asthma and
cystic fibrosis, to insulin for diabetes patients, and needle-free
vaccinations to infants.
The HYDRA research will be published on Thursday 7 January in the scientific journal Advanced Materials.
Source: RMIT University
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