What is the difference in inflammation after bleeds vs. clots?
http://www.alphagalileo.org/ViewItem.aspx?ItemId=160779&CultureCode=en
Nanoparticles from ceria – a rare earth metal – might lessen
inflammation in the brain following a bleeding stroke (hemorrhagic
stroke), according to research presented at the American Stroke
Association’s International Stroke Conference 2016.
Researchers from South Korea noted that previous studies have shown
that ceria nanoparticles have strong antioxidant properties as well as
anti-inflammatory effects. This study investigated whether the tiny
particles could reduce inflammation that occurs just after an
intracerebral hemorrhage (bleeding within the brain).
In a lab experiment, researchers studied a type of white blood cell
called macrophages taken from the brains of rats and applied ceria
nanoparticles to them. Compared with untreated macrophages, the
macrophages treated with the nanoparticles secreted fewer
inflammation-promoting chemicals.
In a second experiment, researchers injected ceria nanoparticles in
10 rats with brain bleeds. Compared with 10 untreated rats, the treated
rats had less damage at the stroke site and less water accumulation,
suggesting less inflammation in the area of the stroke, researchers
said.
http://newsroom.heart.org/news/basic-science-tip-sheet-3127213?preview=288bf38a9020a77868a1001b3426486c
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