Do we need this to support neurogenesis and new stem cells? Build this into the scaffolding needed for stem cells? Ask your doctor.
http://www.alphagalileo.org/ViewItem.aspx?ItemId=163529&CultureCode=en
Large or slow-healing wounds that do not receive adequate
blood flow could benefit from a novel approach that combines a nanoscale
graft onto which three different cell types are layered. Proper cell
alignment on the nanograft allows for the formation of new blood
vessel-like structures, as reported in of Tissue Engineering, Part A, a
peer-reviewed journal from Mary Ann Liebert, Inc., publishers
(http://www.liebertpub.com/). The article is available free for download
on the Tissue Engineering
(http://online.liebertpub.com/doi/full/10.1089/ten.tea.2015.0461)
website until May 26, 2016.
Tae Hee Kim, Soo Hyun Kim, PhD, Kam Leong, PhD, and Youngmee Jung,
PhD, Korea Institute of Science and Technology, Korea University, Korea
University of Science and Technology (Seoul, Korea) and Columbia
University (New York, NY), describe the nanoscale topography and
triculture technology they used to create a microenvironment that mimics
what occurs in normal tissue and can promote angiogenesis. They
demonstrate how the shape, width, and depth of the nanograft all
affected the behavior of the cells and the formation of stable
capillary-like tubular structures.
In the article "Nanografted Substrata and Triculture of Human
Pericytes, Fibroblasts, and Endothelial Cells for Studying the Effects
on Angiogenesis
(http://online.liebertpub.com/doi/full/10.1089/ten.tea.2015.0461)," the
researchers describe how this technique could be applicable for treating
wounds that do not heal well naturally.
"The combination of advanced materials and polycellular
administration is opening new paths to the all-important requirement for
angiogenesis in tissue engineering," says Co-Editor-in-Chief Peter C.
Johnson, MD, Principal, MedSurgPI, LLC and President and CEO,
Scintellix, LLC, Raleigh, NC.
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