Neuroprotective effects of the catalytic subunit of telomerase: A potential therapeutic target in the central nervous system

No clue. You could ask our fucking failures of stroke associations but they won't even know about it much less do any followup research. In case you haven't figured it out yet, you're screwed, your children and grandchildren are screwed unless we destroy the existing stroke organizations and replace them with survivor focused ones.
http://www.ncbi.nlm.nih.gov/pubmed/27095058

González-Giraldo Y¹, Forero DA², Echeverria V³, Gonzalez J¹, Ávila-Rodriguez M⁴, Garcia-Segura LM⁵, Barreto GE⁶.

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Abstract

Senescence plays an important role in neurodegenerative diseases and involves key molecular changes induced by several mechanisms such as oxidative stress, telomere shortening and DNA damage. Potential therapeutic strategies directed to counteract these molecular changes are of great interest for the prevention of the neurodegenerative process. Telomerase is a ribonucleoprotein composed of a catalytic subunit (TERT) and a RNA subunit (TERC). It is known that the telomerase is involved in the maintenance of telomere length and is a highly expressed protein in embryonic stages and decreases in adult cells. In the last decade, a growing number of studies have shown that TERT has neuroprotective effects in cellular and animal models after a brain injury. Significantly, differences in TERT expression between controls and patients with major depressive disorder have been observed. More recently, TERT has been associated with the decrease in reactive oxygen species and DNA protection in mitochondria of neurons. In this review, we highlight the role of TERT in some neurodegenerative disorders and discuss some studies focusing on this protein as a potential target for neuroprotective therapies. (We don't need discussion, we need followup research and if we had a strategy we could get somewhere by following a strategy.)