Intrinsic Control of Axon Regeneration

A whole slew of wonderful diagrams at the link that your doctor can use to explain to you in detail how their stroke protocol on axon regeneration works. Whoops, your doctor has no protocol for anything in stroke does s/he?
http://www.cell.com/neuron/abstract/S0896-6273%2816%2930109-X

Zhigang He

,

Yishi Jin

DOI: http://dx.doi.org/10.1016/j.neuron.2016.04.022

A determinant of axon regeneration is the intrinsic growth ability of injured neurons, which dictates a battery of injury responses in axons and cell bodies. While some of these regulatory mechanisms are evolutionarily conserved, others are unique to the mammalian central nervous system (CNS) where spontaneous regeneration usually does not occur. Here we examine our current understanding of these mechanisms at cellular and molecular terms and discuss their potential implications for promoting axon regeneration and functional recovery after nerve injury.