Tuesday, May 10, 2016

Prescribing multiple neurostimulants during rehabilitation for severe brain injury

But the suggested endpoints of full consciousness are way too general to tell if this works to improve recovery of lost functions. More research needed that will never be done because we have NO fucking strategy or leadership.
http://search.naric.com/research/rehab/redesign_record.cfm?search=2&type=all&criteria=J73441&phrase=no&rec=130355
The Scientific World Journal , Volume 2014(964578)

NARIC Accession Number: J73441.  What's this?
ISSN: 2356-6140.
Author(s): Herrold, Amy A.; Pape, Theresa L.-B.; Guernon, Ann; Mallinson, Trudy; Collins, Eileen; Jordan, Neil.
Project Number: 90SF0004 (formerly H133F130011).
Publication Year: 2014.
Number of Pages: 7.
Abstract: Study investigated whether the number of neurostimulants received during rehabilitation was associated with recovery of full consciousness or improved neurobehavioral function after severe brain injury (BI). Data from 115 participants were extracted from a neurobehavioral observational study database. Univariate optimal data analysis was conducted to determine if the number of neurostimulants influenced classification of four outcomes: recovery of full consciousness during rehabilitation, recovery of full consciousness within one year of injury, and meaningful neurobehavioral improvement during rehabilitation defined as either at least a 4.7 unit (minimal detectable change) or 2.58 unit (minimal clinically important difference) gain on the Disorders of Consciousness Scale-25 (DOCS-25). The results indicated that the number of neurostimulants was not significantly associated with recovery of full consciousness during rehabilitation, within one year of injury, or meaningful neurobehavioral improvement using the DOCS-25. Receiving multiple neurostimulants during rehabilitation may not influence recovery of full consciousness or meaningful neurobehavioral improvement. Given costs associated with additional medication, future research is needed to guide physicians about the merits of prescribing multiple neurostimulants during rehabilitation after severe BI.
Descriptor Terms: BRAIN INJURIES, COMA, DRUGS, MEDICAL TREATMENT, OUTCOMES, PHARMACOLOGY, REHABILITATION.

Can this document be ordered through NARIC's document delivery service*?: Y.
Get this Document: http://www.hindawi.com/journals/tswj/2014/964578/.

Citation: Herrold, Amy A., Pape, Theresa L.-B., Guernon, Ann, Mallinson, Trudy, Collins, Eileen, Jordan, Neil. (2014). Prescribing multiple neurostimulants during rehabilitation for severe brain injury. The Scientific World Journal, 2014(964578) Retrieved 5/10/2016, from REHABDATA database.

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