Prior antithrombotic use is associated with favorable mortality and functional outcomes in acute ischemic stroke

This really is useless, nothing on the amount of the intervention(aspirin size) and nothing on the length of time used. So you will have to do it by the by guess and by golly method just like everything else in stroke.
http://www.mdlinx.com/internal-medicine/medical-news-article/2016/07/26/antiplatelet-agents-antithrombotic-agents-mortality-prognosis/6769817/?
This research was designed to explore the association between prior antithrombotic use with favorable mortality and clinical outcomes in acute ischemic stroke. Findings imply previous antithrombotic therapy was independently associated with improved clinical outcomes after acute ischemic stroke. Guaranteeing the use of antithrombotics in suitable patient populations might be associated with benefits beyond stroke prevention.

Methods

• The authors examined the unadjusted and adjusted associations between previous antithrombotic use and clinical outcomes, using data from Get With The Guidelines–Stroke with over half a million acute ischemic strokes recorded between October 2011 and March 2014 (n=540993) from 1661 hospitals across the United States.

Results

• As per this study, there were 250104 (46%) stroke patients not receiving any antithrombotic before stroke; of whom approximately 1/3^rd had a documented previous vascular indication.
• Patients who were receiving antithrombotics before stroke had better outcomes than those who did not, after controlling for clinical and hospital factors, regardless of whether a previous vascular indication was present or not: adjusted odds ratio (95% confidence intervals) were 0.82 (0.80–0.84) for in–hospital mortality, 1.18 (1.16–1.19) for home as the discharge destination, 1.15 (1.13–1.16) for independent ambulatory status at discharge, and 1.15 (1.12–1.17) for discharge modified Rankin Scale score of 0 or 1.

Go to PubMed Go to Abstract Print Article Summary Cat 2 CME Report