Flavanone intake is inversely associated with risk of incident ischemic stroke in the REasons for Geographic and Racial Differences in Stroke (REGARDS) study

I think this means more Flavanone intake  results in fewer strokes. Which should mean our fucking failures of stroke associations get cracking on a stroke diet protocol with exact amounts to eat. Research is going to be needed to be followed up using stroke survivors.
http://www.mdlinx.com/internal-medicine/medical-news-article/2016/09/26/ischemic-stroke-flavonoid-plant-based-diet/6871965/?news_id=881&newsdt=100116&subspec_id=488&utm_source=WeeklyNL&utm_medium=newsletter&utm_content=Weeks-Best-Article&utm_campaign=article-section&category=latest-weekly

The Journal of Nutrition, 09/26/2016 Goetz ME, et al.

In this study, the researchers conclude that greater utilization of flavanones, but not total or other flavonoid subclasses, was contrarily connected with incident ischemic stroke. In ischemic stroke incidence associations did not differ by sex, race, or region for the association; but, regional differences in flavanone intake may contribute to regional disparities. In blacks higher flavanone intake recommends that flavanone intake is not implicated in racial disparities in ischemic stroke incidence.

Methods

• 20,024 participants were evaluated in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) study, a biracial prospective study.
• They excluded participants with stroke history(WHY?) or missing dietary data.
• They estimated flavonoid intake by using a Block98 food frequency questionnaire and the USDA’s Provisional Flavonoid Addendum and Proanthocyanidin Database.
• They assessed associations between quintiles of flavonoid intake and incident ischemic stroke by using Cox proportional hazards models, adjusting for confounders.

Results

• 524 acute ischemic strokes happened over 6.5 y.
• As per the outcomes, flavanone intake was lower in the Southeastern United States but higher in blacks than in whites.
• Flavanone intake was inversely associated with incident ischemic stroke (HR: 0.72; 95% CI: 0.55, 0.95; P–trend = 0.03), after multivariable adjustment.
• The study observed that consumption of citrus fruits and juices was inversely associated with incident ischemic stroke (HR: 0.69; 95% CI: 0.53, 0.91; P–trend = 0.02).
• No association was found between total flavonoids and other flavonoid subclasses with incident ischemic stroke.
• The study reveal that there was no statistical interaction with sex, race, or region for any flavonoid measure.

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