Friday, November 4, 2016

Meta‐Analysis of Potassium Intake and the Risk of Stroke

This has been known for years. Why the fuck hasn't a protocol been written and disseminated to all doctors and stroke survivors?  I bet nothing is done after this either, incompetence is rampant in stroke.

Daily potassium intake and sodium-to-potassium ratio in the reduction of blood pressure: a meta-analysis of randomized controlled trials  July 2015


Effect of high potassium diet on endothelial function  June 2014

Slash Risk of Stroke with More Potassium and Less Salt  June 2013

Why eat three bananas a day?    April 2012

The latest here:

Meta‐Analysis of Potassium Intake and the Risk of Stroke

Marco Vinceti, Tommaso Filippini, Alessio Crippa, Agnès de Sesmaisons, Lauren A. Wise and Nicola Orsini

Abstract

Background The possibility that lifestyle factors such as diet, specifically potassium intake, may modify the risk of stroke has been suggested by several observational cohort studies, including some recent reports. We performed a systematic review and meta‐analysis of existing studies and assessed the dose–response relation between potassium intake and stroke risk.
Methods and Results We reviewed the observational cohort studies addressing the relation between potassium intake, and incidence or mortality of total stroke or stroke subtypes published through August 6, 2016. We carried out a meta‐analysis of 16 cohort studies based on the relative risk (RR) of stroke comparing the highest versus lowest intake categories. We also plotted a pooled dose–response curve of RR of stroke according to potassium intake. Analyses were performed with and without adjustment for blood pressure. Relative to the lowest category of potassium intake, the highest category of potassium intake was associated with a 13% reduced risk of stroke (RR=0.87, 95% CI 0.80–0.94) in the blood pressure–adjusted analysis. Summary RRs tended to decrease when original estimates were unadjusted for blood pressure. Analysis for stroke subtypes yielded comparable results. In the spline analysis, the pooled RR was lowest at 90 mmol of potassium daily intake (RRs=0.78, 95% CI 0.70–0.86) in blood pressure–adjusted analysis, and 0.67 (95% CI 0.57–0.78) in unadjusted analysis.
Conclusions Overall, this dose–response meta‐analysis confirms the inverse association between potassium intake and stroke risk, with potassium intake of 90 mmol (≈3500 mg)/day associated with the lowest risk of stroke.

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