Wednesday, December 14, 2016

Dietary magnesium intake and the risk of cardiovascular disease, type 2 diabetes, and all-cause mortality: A dose-response meta-analysis of prospective cohort studies

Useless information unless the full article gives the foods used. I.E. a diet protocol. This is so fucking simple, create protocols for every intervention. Who cares if they haven't been totally proven out? Update them as more information comes in. But the perfect is better than the good enough, so don't expect anything useful from the current mindset for 50 years.
https://www.mdlinx.com/internal-medicine/medical-news-article/2016/12/14/magnesium-cardiovascular-disease-type-2-diabetes/6975741/?
BMC Medicine, 12/14/2016
For this study, researchers directed a dose–response meta–analysis of prospective cohort studies keeping in mind the end goal to research the relationship between's magnesium consumption and the risk of cardiovascular disease (CVD), type 2 diabetes (T2D), and all–cause mortality. Expanding dietary magnesium consumption is connected with a diminished risk of stroke, heart failure, diabetes, and all–cause mortality, but not CHD or total CVD. These discoveries bolster the idea that expanding dietary magnesium may give health benefits.

Methods

  • In this study researchers searched PubMed, EMBASE, and Web of Science for articles.
  • They searched articles that contained risk estimates for the outcomes of interest and were published through May 31, 2016.
  • The pooled results were examined utilizing a random–effects model.

Results

  • 40 prospective cohort studies totaling more than 1 million participants were incorporated into the examination.
  • Amid the follow–up periods (ranging from 4 to 30 years), 7678 cases of CVD, 6845 cases of coronary heart disease (CHD), 701 cases of heart failure, 14,755 cases of stroke, 26,299 cases of T2D, and 10,983 deaths were reported.
  • No significant affiliation was seen between expanding dietary magnesium consumption (per 100 mg/day increment) and the risk of total CVD (RR: 0.99; 95% CI, 0.88–1.10) or CHD (RR: 0.92; 95% CI, 0.85–1.01).
  • However, the same incremental increase in magnesium consumption was connected with a 22% diminishment in the risk of heart failure (RR: 0.78; 95% CI, 0.69–0.89) and a 7% reduction in the risk of stroke (RR: 0.93; 95% CI, 0.89–0.97).
  • Besides, the outline relative risks of T2D and mortality per 100 mg/day increment in magnesium consumption were 0.81 (95% CI, 0.77–0.86) and 0.90 (95% CI, 0.81–0.99), respectively.
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