Tuesday, January 3, 2017

Effects of pomegranate juice on blood pressure: A systematic review and meta-analysis of randomized controlled trials

Is this better than the vascular effects of coffee? We'll never know because not one single person in the world wants to tackle these extremely difficult questions that might help stroke survivors. You're screwed. Don't do this on your own and don't listen to me, I get the pomegranate/cranberry blend.

Effects of pomegranate juice on blood pressure: A systematic review and meta-analysis of randomized controlled trials

Pharmacological Research , 12/06/2016
In this study, researchers systematically review and meta–analyze accessible proof from randomized placebo–controlled trials (RCTs) researching the impacts of pomegranate juice intake and blood pressure (BP). The present meta–analysis recommends consistent benefits of pomegranate juice intake on BP. This evidence recommends it might be prudent to include this fruit juice in a heart–healthy diet.
  • A comprehensive literature look in Medline and Scopus was completed to distinguish qualified RCTs.
  • A meta–analysis of qualified reviews was performed utilizing a random–effects model.
  • Quality assessment, sensitivity analysisand publication bias assessments were led utilizing standard methods.
  • Quantitative information synthesis from 8 RCTs indicated significant decreases in both systolic [weighed mean difference (WMD): –4.96 mmHg, 95% CI: –7.67 to –2.25, p < 0.001) and diastolic BP (WMD: –2.01 mmHg, 95% CI: –3.71 to –0.31, p = 0.021) after pomegranate juice intake.
  • Consequences for SBP stayed stable to sensitivity investigations.
  • Pomegranate juice diminished SBP regardless of the duration (>12 wks: WMD = –4.36 mmHg, 95% CI: –7.89 to –0.82, p = 0.016) and <12 wks: WMD = –5.83 mmHg, 95% CI: –10.05 to –1.61, p = 0.007) and dose consumed (>240 cc: WMD = -3.62 mmHg, 95% CI: –6.62 to –0.63, p = 0.018) and <240 cc: WMD = –11.01 mmHg, 95% CI: –17.38 to –4.65, p = 0.001, pomegranate juice per day) whereas doses >240 cc provided a borderline significant impact in lessening DBP.
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