Neural plasticity and network remodeling: from concepts to pathology

Does your doctor already know exactly how to get neuroplasticity to work in your stroke rehab? The emphasis is on EXACTLY. Not just this generalized crap that you need to get neuroplasticity to work for you. A protocol would be perfect.

Neural plasticity and network remodeling: from concepts to pathology

Neuroscience, Volume 344, Issue null, Pages 326-345
Erez James Cohen, Eros Quarta, Riccardo Bravi, Alberto Granato, Diego Minciacchi

Abstract

Neuroplasticity has been subject to a great deal of research in the last century. Recently, significant emphasis has been placed on the global effect of localized plastic changes throughout the central nervous system, and on how these changes integrate in a pathological context. Specifically, alterations of network functionality have been described in various pathological contexts to which corresponding structural alterations have been proposed. However, considering the amount of literature and the different pathological contexts, an integration of this information is still lacking. In this paper we will review the concepts of neural plasticity as well as their repercussions on network remodeling and provide a possible explanation to how these two concepts relate to each other. We will further examine how alterations in different pathological contexts may relate to each other and will discuss the concept of plasticity diseases, its models and implications.