Effects of different exercise strategies and intensities on memory performance and neurogenesis

Maybe there is a protocol in the full article but I doubt it, making this totally useless.
http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00047/abstract

Kai Diederich^1*, Anna Bastl¹, Heike Wersching², Anja Teuber², Jan-Kolja Strecker¹, Antje Schmidt¹, Jens Minnerup¹ and Wolf-Rüdiger Schäbitz³

• ¹Department of Neurology, University of Münster, Germany
• ²Institute of Epidemiology and Social Medicine, University of Münster, Germany
• ³Department of Neurology, Evangelisches Krankenhaus Bielefeld, Germany

It is well established that physical exercise affects both hippocampal neurogenesis and memory functions. Until now, distinctive effects of controlled and voluntary training on behavior and neurogenesis as well as interactions between exercise intensity, neurogenesis and memory performance are still elusive. The present study tested the impact of moderate controlled and voluntary training on memory formation and hippocampal neurogenesis and evaluated interactions between exercise performance, learning efficiency and proliferation of progenitor cells in the hippocampus.
Our data show that both controlled and voluntary training augmented spatial learning and promoted hippocampal neurogenesis. Regression analysis revealed a significant linear increase of the amount of new hippocampal neurons with increased exercise intensity. Regression analysis of exercise performance on retention memory performance revealed a quadratic, inverted u-shaped relationship between exercise performance and retention of spatial memory. No association was found between the amount of newborn neurons and memory performance.
Our results demonstrate that controlled training, if performed with an appropriate combination of speed and duration, improves memory performance and neurogenesis. Voluntary exercise elevates neurogenesis dose dependently to high levels. Best cognitive improvement was achieved with moderate exercise performance.

Keywords: Exercise, Hippocampal neurogenesis, Learning, Memory, Regression Analysis
Citation: Diederich K, Bastl A, Wersching H, Teuber A, Strecker J, Schmidt A, Minnerup J and Schäbitz W (2017). Effects of different exercise strategies and intensities on memory performance and neurogenesis. Front. Behav. Neurosci. 11:47. doi: 10.3389/fnbeh.2017.00047