Sunday, November 12, 2017

Drug Caused Arterial Plaque in Mice to 'Melt Away' (CNBC)

You'll have to wait decades before any followup is done. It mentions coronary not cerebral so our stroke medical professionals will never put two and two together and decide this might help prevent stroke also.
https://www.medpagetoday.com/cardiology/atherosclerosis/69027

Regression observed after initial dos

  • by
Atherosclerotic plaque in mice began to "melt away" after a single dose of the investigational drug trodusquemine, CNBC reported.
Researchers at the University of Aberdeen in Scotland studied mice that had established coronary atherosclerosis. The animals received either trodusquemine or standard treatment, and the amount of atherosclerotic plaque was measured before and after treatment. Plaque regressed significantly after the initial dose of trodusquemine, a protein tyrosine phosphatase 1B inhibitor also evaluated as a treatment for cancer and diabetes.

"These have only been tested at the preclinical level, in mice, so far, but the results were quite impressive and showed that just a single dose of this drug seemed to completely reverse the effects of atherosclerosis," said principal investigators Mirela Delibegovic, PhD, adding that investigators plan to test the drug in humans.

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