Sunday, December 10, 2017

Assessment of disuse atrophy during periods of prolonged bed rest in patients with mild ischemic stroke with bioelectrical impedance analysis

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Assessment of disuse atrophy during periods of prolonged bed rest in patients with mild ischemic stroke with bioelectrical impedance analysis


Background: 
We keep acute cerebral infarction patients in bed for several days to maintain cerebral blood flow.
Objective: 
We studied whether disuse atrophy occurs during the bed rest period in the patients with mild ischemic stroke.
Patients and Methods/Material and Methods: 
We investigated 26 patients who were admitted to our hospital from Oct 2015 to March 2017. Their National Institutes of Health Stroke Scale score was under 7, and they were under 80 years old and gave consent. We treated them with 4 days in the supine position, and after that we gradually raised the upper half of their beds to angle of 90 degrees. We administrated rehabilitation during this period. We investigated them with bioelectrical impedance analysis (BIA) over a 7 cm below and above section from the center of the thigh, and obtained the muscle cross sectional area index (MCAI), which reflects muscle volume. Measurements were taken 2 to 3 times over a period of 5 days. Any data, which changed more than or less than 20 % from the previous measurement data was excluded. We analyzed the first and last day of the 5 days data period using the paired t-test. This study was carried out in accordance with the Human Research Guideline of the Internal Ethics Review Board of our hospital.
Results: 
The averaged MCAI impaired side did not change significantly from 0.821 to 0.804 (p=0.249).
Conclusion: 
In the patients with mild cerebral stroke, the administration of bed-side rehabilitation may prevent the occurrence of the disuse atrophy during the bed rest period.

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