Cognitive and mood improvements following acute supplementation with purple grape juice in healthy young adults

It would take a lot to extrapolate this to most stroke survivors, they aren't healthy or young. But the real question to be answered; is red wine even better than grape juice for cognition and mood improvements? Both are sorely needed for stroke survivors, When will followup and an updated diet protocol occur?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682870/

C. F. Haskell-Ramsay,¹ R. C. Stuart,¹ E. J. Okello,² and A. W. Watson²

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This article has been corrected. See Eur J Nutr. 2017 October 06; : .

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Abstract

Purpose

Berry-derived phenolic compounds found in grapes have been associated with a number of health benefits, including the augmentation of human brain function and cognition. Previous intervention studies of Concord grape juice have demonstrated improvement to memory and driving ability following 3- to 4-month supplementation in middle-aged and older adults. However, no studies to date have demonstrated acute cognitive benefits of grape juice, and investigation of these effects in young adults is lacking.

Methods

This randomised, placebo-controlled, double-blind, counterbalanced-crossover study, assessed the effects of 230 ml purple grape juice or sugar-matched control in 20 healthy young adults. Computerised measures of episodic memory, working memory, attention and mood were completed at baseline and following a 20-min absorption period.

Results

Purple grape juice significantly improved reaction time on a composite attention measure (p = 0.047) and increased calm ratings (p = 0.046) when compared to placebo. Order effects also indicated an enduring positive effect on pre-dose memory reaction time (p = 0.018) and post-dose calm ratings (p = 0.019) when purple grape was consumed first.

Conclusions

These findings in a small sample of healthy young adults suggest that purple grape juice can acutely enhance aspects of cognition and mood. No significant effects of juice were observed on memory measures, suggesting that these may be less susceptible to manipulation following acute supplementation in healthy young adults. Potential mechanisms underlying these effects include modulation of cerebral blood flow, glucoregulation and inhibition of monoamine oxidase activity, all of which require further exploration.