Sunday, August 12, 2018

Brain area responsible for pessimism found

What is your doctor doing to bring back your pessimism area?

Pessimists May Live Longer


https://www.medicalnewstoday.com/articles/322741.php
Neuroscientists have now found the brain area responsible for pessimism. The new research suggests that both anxiety and depression are caused by an overstimulation of the caudate nucleus.
Researchers may have found the brain area that drives negative thinking.
Looking at mice, our fellow mammals, can offer important insights into human behavior.
A new study, published in the journal Neuron, examines the neurological underpinnings of pessimism in mice and also finds clues about anxiety and depression in humans.
The new research was led by senior researcher Ann Graybiel, a professor at the Massachusetts Institute of Technology in Cambridge.
Prof. Graybiel and colleagues focused on a type of decision-making process known as approach-avoidance conflict.
Approach-avoidance conflict describes situations in which people (or mammals) have to decide between two options by weighing the positive and negative aspects of each alternative.
Previous research that Prof. Graybiel conducted with her team found the brain circuits responsible for this kind of decision-making. They then found that having to decide in this scenario can induce significant stress, and that chronic stress makes rodents choose the riskier option that has the highest potential reward.

The caudate nucleus and decision-making

In the new study, to recreate the scenario in which rodents have to choose by weighing positives and negatives, the scientists offered mice a squirt of juice as a reward but coupled it with an aversive stimulus: a puff of air in the face.
Over several trials, the researchers varied the ratio of reward to unpleasant stimuli and gave the rodents the ability to choose whether to accept the reward with the aversive stimulus or not.

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