Evolution of Cortical Asymmetry with Post-stroke Rehabilitation: A Pilot Study

Just why the fuck are you looking at recovery predictions? Rather than solving all the problems in stroke and writing stroke rehab protocols? Laziness? Incompetence? Or just don't care? No leadership? No strategy? Not my job?

 

Evolution of Cortical Asymmetry with Post-stroke Rehabilitation: A Pilot Study

• Authors
• Authors and affiliations

• Jenifer Miehlbradt
• Camilla Pierella
• Nawal Kinany
• Martina Coscia
• Elvira Pirondini
• Matteo Vissani
• Alberto Mazzoni
• Cécile Magnin
• Pierre Nicolo
• Adrian G. Guggisberg
• Silvestro Micera

• Jenifer Miehlbradt
  • 1
  Email author
• Camilla Pierella
  • 1
• Nawal Kinany
  • 1
  • 3
  • 4
• Martina Coscia
  • 2
• Elvira Pirondini
  • 3
  • 4
• Matteo Vissani
  • 5
• Alberto Mazzoni
  • 5
• Cécile Magnin
  • 6
• Pierre Nicolo
  • 6
  • 7
• Adrian G. Guggisberg
  • 6
  • 7
• Silvestro Micera
  • 1
  • 5

1. 1.Bertarelli Foundation Chair in Translational Neuroengineering, Center for Neuroprosthetics, École Polytechnique Fédérale de Lausanne (EPFL)GenevaSwitzerland
2. 2.Wyss Center for Bio- and NeuroengineeringGenevaSwitzerland
3. 3.Institute of Bioengineering/Center for Neuroprosthetics, Ecole Polytechnique Fédérale de Lausanne (EPFL)LausanneSwitzerland
4. 4.Department of Radiology and Medical InformaticsUniversity of GenevaGenevaSwitzerland
5. 5.Biorobotics Institute, Scuola Superiore Sant’AnnaPisaItaly
6. 6.Division of Neurorehabilitation, Department of Clinical NeurosciencesUniversity Hospital GenevaGenevaSwitzerland
7. 7.Laboratory of Cognitive Neurorehabilitation, Department of Clinical Neurosciences, Medical School, University of GenevaGenevaSwitzerland

Conference paper

First Online: 16 October 2018

Part of the Biosystems & Biorobotics book series (BIOSYSROB, volume 21)

Abstract

The lesions induced by unilateral strokes perturb the complex and critical interhemispheric balance. While a high asymmetry measured in the acute phase is known to be a predictor for poor motor recovery, the evolution of this imbalance along motor recovery has not been studied. Here, we evaluated the evolution of the cortical power asymmetry during a robot-assisted motor task along a rehabilitation intervention. Preliminary results suggest that a reduction of the brain asymmetry towards values exhibited by healthy controls is associated with higher motor recovery.

Research supported by the Wyss Center for Bio- and Neuro- Engineering and the Bertarelli Foundation Chair in Translational Neuroengineering.

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