Abstract
Background and Purpose—
Intracerebral
hemorrhage (ICH) has a poorer prognosis than acute ischemic stroke
(AIS). However, clinician perception of prognosis may influence
treatment decisions and adversely affect outcome. On acute CT, the
conspicuity of ICH compared with AIS may lead clinicians to overestimate
severity and influence prognostic evaluation. We investigated whether
clinicians’ estimates of volume, severity, and prognosis from acute
imaging differed between ICH and AIS.
Methods—
CT
scans from participants with acute ICH or ischemic stroke were
reviewed. Volume was calculated using the ABC/2 method and automated
volumetric analysis via specialized imaging software. ICH cases were
matched with AIS cases for lesion volume, based on acute (<6 hours)
CT for ICH, and 24-hour CT for AIS. Blind to clinical information,
clinicians estimated lesion volume to the nearest 5 mL, graded lesion
severity from 1 (mild) to 5 (very severe), and estimated 30-day
prognosis using the modified Rankin Scale.
Results—
We
compared 33 ICH cases with 33 volume-matched AIS cases. Clinicians
overestimated ICH volume and underestimated AIS volumes: mean
differences (estimated−actual volume) were +8 mL (±30) for ICH and −8 mL
(±27) for AIS (P<0.001). Observers rated ICH to be of greater
severity and poorer prognosis compared with AIS cases: 109 of 265 (41%)
ICH cases rated severity categories 4 or 5 compared with 36 of 257
(14%) AIS, P<0.001; estimated modified Rankin Scale of 0 to 2 in 125 of 265 (47%) ICH compared with 190 of 257 (74%) AIS, P<0.001.
Results were unaffected by presence of intraventricular blood.
Estimated severity and prognosis for ICH remained significantly worse
compared with AIS after adjustment for estimated volumes.
Conclusions—
Clinicians
overestimated ICH volume and severity compared with AIS of equivalent
volume and also assigned significantly worse prognosis independent of
volume estimates.
No comments:
Post a Comment