Objective:
We
assessed whether providing detailed clinical information alongside
computed tomography (CT) images improves their interpretation for acute
stroke.
Methods:
Using
the prospective Cornell AcutE Stroke Academic Registry, we randomly
selected 100 patients who underwent noncontrast head CT within 6 hours
of transient ischemic attack or minor acute ischemic stroke and
underwent magnetic resonance imaging (MRI) within 6 hours of the CT.
Three radiologist investigators evaluated each of the 100 CT studies
twice, once with and once without accompanying information on medical
history, signs, and symptoms. In random sequence, each study was
interpreted in one condition (ie, with or without detailed accompanying
information) and then after a 4-week washout period, in the opposite
condition. Using MRI diffusion-weighted imaging (DWI) as the reference
standard, we classified CT interpretations as correct (true positives or
negatives) or incorrect (false positives or negatives). We used
logistic regression with sandwich estimators to compare the proportion
of correct interpretations.
Results:
In
patients with DWI-defined infarcts, acute ischemia was called on 20% of
CTs with detailed history and 18% without history. In patients without
infarcts, the absence of ischemia was called on 77% of CTs with history
and 77% without history. The proportion of correct interpretations of
CTs accompanied by detailed clinical history (49%) did not differ
significantly from those without history (47%; odds ratio: 1.1; 95%
confidence interval: 0.8-1.4).
Conclusions:
Reported
findings on head CT for evaluation of suspected acute ischemic stroke
were similar regardless of whether detailed clinical history was
provided.
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