Monday, February 4, 2019

Effect of balloon guide catheter on clinical outcomes and reperfusion in Trevo thrombectomy

Wrong endpoints measured. Survivors don't give a shit about; 

  1. groin puncture time

  2. reperfusion time

  3. first pass effect

  4. number of passes 

  5. Didn't even measure how close to 100% recovery survivors got. 

Effect of balloon guide catheter on clinical outcomes and reperfusion in Trevo thrombectomy

  1. Thanh N Nguyen1,2,3,
  2. Alicia C Castonguay4,
  3. Raul G Nogueira5,
  4. Diogo C Haussen5,
  5. Joey D English6,
  6. Sudhakar R Satti7,
  7. Jennifer Chen8,
  8. Hamed Farid9,
  9. Candace Borders10,
  10. Erol Veznedaroglu11,
  11. Mandy J Binning11,
  12. Ajit S Puri12,
  13. Nirav A Vora13,
  14. Ron F Budzik13,
  15. Guilherme Dabus14,
  16. Italo Linfante14,
  17. Vallabh Janardhan15,
  18. Amer Alshekhlee16,
  19. Michael G Abraham17,
  20. Randall C Edgell18,
  21. M Asif Taqi19,
  22. Ramy El Khoury20,
  23. Maxim Mokin21,
  24. Aniel Q Majjhoo22,
  25. Mouhammed R Kabbani23,
  26. Michael T Froehler24,
  27. Ira Finch25,
  28. Sameer A Ansari26,
  29. Roberta Novakovic27,
  30. Mohamad Abdalkader1,2,3,
  31. Osama O Zaidat28

Author affiliations


Abstract

Introduction The Solitaire stent retriever registry showed improved reperfusion, faster procedure times, and better outcome in acute stroke patients with large vessel occlusion treated with a balloon guide catheter (BGC) and Solitaire stent retriever compared with a conventional guide catheter. The goal of this study was to evaluate whether use of a BGC with the Trevo stent retriever improves outcomes compared with a conventional guide catheter.
Methods The TRACK registry recruited 23 sites to submit demographic, clinical, and site adjudicated angiographic and outcome data on consecutive patients treated with the Trevo stent retriever. BGC use was at the discretion of the physician.
Results 536 anterior circulation patients (of whom 279 (52.1%) had BGC placement) were included in this analysis. Baseline characteristics were notable for younger patients in the BGC group (65.4±15.3 vs 68.1±13.6, P=0.03) and lower rate of hypertension (72% vs 79%, P=0.06). Mean time from symptom onset to groin puncture was longer in the BGC group (357 vs 319 min, P=0.06).Thrombolysis in Cerebral Infarction 2b/3 scores were higher in the BGC cohort (84% vs 75.5%, P=0.01). There was no difference in reperfusion time, first pass effect, number of passes, or rescue therapy. Good clinical outcome(What the fuck is your definition of this? Mine is 100% recovery.) at 3 months was superior in patients with BGC (57% vs 40%; P=0.0004) with a lower mortality rate (13% vs 23%, P=0.008). Multivariate analysis demonstrated that BGC use was an independent predictor of good clinical outcome (OR 2; 95% CI 1.3 to 3.1, P=0.001).
Conclusions In acute stroke patients presenting with anterior circulation large vessel occlusion, use of a BGC with the Trevo stent retriever resulted in improved reperfusion, improved clinical outcome, and lower mortality.

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