Thursday, August 22, 2019

Association of intensive vs standard blood pressure control with cerebral white matter lesions

My doctor told me I had a bunch of white matter lesions right after my stroke. He never showed me any scans so he might have just been pulling crap out of his ass. In today's world this should be a protocol to intensively treat blood pressure. But I'm sure your doctor and stroke hospital are incompetent and won't have this in place in the next month. It is YOUR RESPONSIBILITY to train your doctor in this. Otherwise it will never get done.  And you will bear the burden of this problem while your doctor doesn't face any consequences for incompetency. 

Oops, my bad. Suggesting I know more than your doctor. Don't listen to me I'm not medically trained, but I do keep up with research.

Association of intensive vs standard blood pressure control with cerebral white matter lesions

JAMA | August 15, 2019

The SPRINT MIND Investigators for the SPRINT Research Group - Via performing a sub-study of a randomized clinical trial that included 449 hypertensive individuals with longitudinal brain MRI, researchers assessed the correlation of intensive blood pressure treatment with cerebral white matter lesion and brain volumes. Mean white matter lesion volume progressed from 4.57 to 5.49 cm3 vs a rise from 4.40 to 5.85 cm3 in the standard treatment group. Mean total brain volume reduced from 1,134.5 to 1,104.0 cm3 in the intensive treatment group vs a drop from 1,134.0 to 1,107.1 cm3 in the standard treatment group. Hence, among hypertensive adults, targeting a systolic blood pressure of < 120 mmHg vs < 140 mm Hg was significantly related to a smaller increase in cerebral white matter lesion volume and a higher reduction in total brain volume; however, the variations were small.
Read the full article on JAMA

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