Eating More Ketones May Fight Against Alzheimer's Disease

You may need this, has your doctor had the nutritionist create a diet protocol on this for hospital food and then at discharge?

Your chances of getting dementia.

1. A documented 33% dementia chance post-stroke from an Australian study?   May 2012.

2. Then this study came out and seems to have a range from 17-66%. December 2013.

3. A 20% chance in this research.   July 2013.

4. Dementia Risk Doubled in Patients Following Stroke September 2018 

5. Parkinson’s Disease May Have Link to Stroke March 2017

The latest here:

Eating More Ketones May Fight Against Alzheimer's Disease

 Early in the development of Alzheimer's disease, the brain becomes over excited, potentially through the loss of inhibitory, or GABAergic, interneurons that keep other neurons from signaling too much. Because interneurons require more energy compared to other neurons, they may be more susceptible to dying when they encounter the Alzheimer's disease protein amyloid beta. Amyloid beta has been shown to damage mitochondria -- the metabolic engine for cells -- by interfering with SIRT3, a protein that preserves mitochondrial functions and protects neurons.

Article continued below...

Ketones Better for Alzheimer's Neurons

Cheng et al. genetically reduced levels of SIRT3 in mouse models of Alzheimer's disease.

Mice with low levels of SIRT3 experienced a much higher mortality rate, more violent seizures, and increased interneuron death compared to the mice from the standard Alzheimer's disease model and control mice. However, the mice with reduced levels of SIRT3 experienced fewer seizures and were less likely to die when they ate a diet rich in ketones, a specific type of fatty acid. The diet also increased levels of SIRT3 in the mice.

Increasing SIRT3 levels via ketone consumption may be a way to protect interneurons and delay the progression of Alzheimer's disease.

Check out this series of videos and articles on using ketones, mct oil and coconut oil for Alzheimer's and dementia.

REFERENCE:

• Aiwu Cheng, Jing Wang, Nathaniel Ghena, Qijin Zhao, Isabella Perone, M. Todd King, Richard L. Veech, Myriam Gorospe, Ruiqian Wan, Mark P. Mattson. SIRT3 Haploinsufficiency Aggravates Loss of GABAergic Interneurons and Neuronal Network Hyperexcitability in an Alzheimer's Disease Model. The Journal of Neuroscience, 2019; 1446-19 DOI: 10.1523/JNEUROSCI.1446-19.2019

SOURCE:

• Society for Neuroscience