Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 31,940 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke. DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Tuesday, February 4, 2020
Abbott to test its heart device against lifetime blood thinners for reducing stroke risk
For those of you with atrial fibrillation, discuss with your doctor.
Abbott plans to launch a
head-to-head study that puts its structural heart device up against a
newer generation of blood thinners, testing its ability to lower the
risk of strokes in people with atrial fibrillation.
The devicemaker’s Amplatzer Amulet occluder is designed to
permanently block a small, naturally forming pouch that develops within
the muscle wall of the heart’s left atrium. In people with an irregular
pulse, this appendage can fail to drain completely with each heartbeat;
the blood that pools there can form clots that, once loose and pumped
out of the heart, can cause debilitating or fatal strokes.
The randomized study, dubbed CATALYST,
will evaluate the device’s performance over at least two years compared
to blood thinners known as non-vitamin K antagonist oral
anticoagulants, or NOACs, and as an alternative to the lifetime regimens
that currently serve as a standard-of-care for patients with AFib.
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This class of drugs includes blockbusters like
Eliquis, Xarelto and Pradaxa, which are now recommended over warfarin
in cardiology treatment guidelines.
"A device that can address a significant structural issue of the
heart via a minimally invasive procedure would be a significant step
forward for patients with atrial fibrillation eligible for long-term
NOAC therapy," said the study’s principal investigator, Vivek Reddy,
director of Cardiac Arrhythmia Services for The Mount Sinai Hospital. RELATED: Abbott names new CFO shortly ahead of CEO transition
The Amplatzer Amulet occluder. (Abbott)
Starting next month, the study plans to enroll up to 2,650
participants at 150 global sites, measuring rates of ischemic strokes,
embolisms or cardiovascular mortality, as well as major bleeding events.
Delivered to the heart by a catheter, the Amplatzer Amulet previously
received a CE mark in 2013.
"The CATALYST trial has the potential to provide data for the
Amplatzer Amulet LAA Occluder that could change clinical practice by
eliminating a lifetime need for blood thinners—reinforcing our mission
of helping people live better lives through better health,” Neil Moat,
chief medical officer of Abbott’s structural heart business, said in a statement.
Abbott estimates that the prevalence of atrial fibrillation will rise
over the coming decade to at least 12.1 million cases, with strokes
related to AFib being nearly twice as fatal compared to unrelated
strokes.
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