Relationship Between Exercise and Alzheimer’s Disease: A Narrative Literature Review

With your excellent chance of getting dementia your doctor is required to get you recovered enough to do higher physical activity levels. YOUR DOCTOR'S RESPONSIBILITY. Don't let them weasel out of that responsibility, you need exact protocols, NOT GUIDELINES. 

Your chances of getting dementia.

1. A documented 33% dementia chance post-stroke from an Australian study?   May 2012.

2. Then this study came out and seems to have a range from 17-66%. December 2013.

3. A 20% chance in this research.   July 2013.

4. Dementia Risk Doubled in Patients Following Stroke September 2018 

5. Parkinson’s Disease May Have Link to Stroke March 2017 

The latest here:

Relationship Between Exercise and Alzheimer’s Disease: A Narrative Literature Review

Qing Meng^1,2, Muh-Shi Lin^3,4,5,6 and I-Shiang Tzeng^7*

• ¹School of Physical Education, Huaqiao University, Quanzhou, China
• ²Sport and Health Research Center, Huaqiao University, Quanzhou, China
• ³Department of Biotechnology and Animal Science, College of Bioresources, National Ilan University, Yilan, Taiwan
• ⁴Division of Neurosurgery, Department of Surgery, Kuang Tien General Hospital, Taichung, Taiwan
• ⁵Department of Biotechnology, College of Medical and Health Care, HungKuang University, Taichung, Taiwan
• ⁶Department of Health Business Administration, College of Medical and Health Care, HungKuang University, Taichung, Taiwan
• ⁷Department of Exercise and Health Promotion, College of Education, Chinese Culture University, Taipei, Taiwan

This narrative review aimed to summarize evidence regarding the responses to exercise among patients with preclinical Alzheimer’s disease (AD) and the effectiveness of long-term exercise interventions in improving cognitive function and neuropsychiatric symptoms. We performed a narrative review of existing literature on the effectiveness of long-term exercise interventions in improving cognitive function and neuropsychiatric symptoms in patients with AD. Patients with AD who presented with long-term exercise interventions appeared to have improved blood flow, increased hippocampal volume, and improved neurogenesis. Most prospective studies have proven that physical inactivity is one of the most common preventable risk factors for developing AD and that higher physical activity levels are associated with a reduced risk of AD development. Physical exercise seems to be effective in improving several neuropsychiatric symptoms of AD, notably cognitive function. Compared with medications, exercise has been shown to have fewer side effects and better adherence.

Background

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by memory loss and multiple cognitive disorders (Reddy and Oliver, 2019). This symptom is the most frequent cause of neurogenesis. Individuals with AD develop progressive mild cognitive impairment (MCI), leading to the development of neuropsychiatric manifestations. Agitation and anxiousness are common complications in individuals diagnosed with AD. Other complications such as bladder and bowel problems, depression, infection, and head trauma or broken bones are the main cause of imbalance and incoordination in these patients (Higuera, 2016).

Alzheimer’s disease is associated with common causes of dementia and is estimated to account for 60–80% of these cases (Alzheimer’s Association [AA], 2016). Aging can be treated as the greatest risk factor for AD progression. About 81% of AD patients are aged over 75 years as estimated by the Alzheimer’s Association [AA], 2016). The diagnosis and treatment of AD involves many challenges. Studies have shown that drug combinations are effective and that there is no efficient treatment for patients diagnosed with preclinical AD or MCI. With respect to the definition of MCI, it is regarded as a syndrome of cognitive decline that is higher than the expectation of the age of individual and level of education without significantly obstructing with daily living activities. Notably, it develops into AD during 5 years in over half of the MCI patients (Gauthier et al., 2006). Based on the possibility of side effects of drugs, people are very interested in the non-pharmacological treatment of AD (Raggi et al., 2017).

Inconsistent benefits of treatments, comprising cognitive training and cognitive stimulation, have been reported. There is an intension to prevent and treat AD, MCI, and dementia via regular exercise (Laurin et al., 2001; Lindsay et al., 2002; Andel et al., 2008). This article aims to review important studies with this scope and consider the association of exercise and AD in patients.