You may have heard about low vitamin D and COVID-19, Well you'll have to get out in the sun. Although Ireland is pushing supplements in this article:
Vitamin D determines severity in COVID-19 so government advice needs to change
This statement on this review from Naveed Saleh,MD is the reason.
But, before we get to that, you might be wondering whether the health benefits of sunlight can be obtained through the convenience of vitamin D supplements. Sadly, according to current research, the answer is no. In a review article published in Lancet Diabetes Endocrinology, for instance, researchers noted that although prospective studies support an association between serum levels of 25-hydroxyvitamin D (25[OH]D)—the principal type of vitamin D circulating in the blood—and various types of chronic disease, interventional studies involving vitamin D supplements do not corroborate such findings.
The latest here:
Vitamin D status and ill health: a systematic review
Published:December 06, 2013DOI:https://doi.org/10.1016/S2213-8587(13)70165-7
Summary
Low serum concentrations of 25-hydroxyvitamin D (25[OH]D) have been associated with
many non-skeletal disorders. However, whether low 25(OH)D is the cause or result of
ill health is not known. We did a systematic search of prospective and intervention
studies that assessed the effect of 25(OH)D concentrations on non-skeletal health
outcomes in individuals aged 18 years or older. We identified 290 prospective cohort
studies (279 on disease occurrence or mortality, and 11 on cancer characteristics
or survival), and 172 randomised trials of major health outcomes and of physiological
parameters related to disease risk or inflammatory status. Investigators of most prospective
studies reported moderate to strong inverse associations between 25(OH)D concentrations
and cardiovascular diseases, serum lipid concentrations, inflammation, glucose metabolism
disorders, weight gain, infectious diseases, multiple sclerosis, mood disorders, declining
cognitive function, impaired physical functioning, and all-cause mortality. High 25(OH)D
concentrations were not associated with a lower risk of cancer, except colorectal
cancer. Results from intervention studies did not show an effect of vitamin D supplementation
on disease occurrence, including colorectal cancer. In 34 intervention studies including
2805 individuals with mean 25(OH)D concentration lower than 50 nmol/L at baseline
supplementation with 50 μg per day or more did not show better results. Supplementation
in elderly people (mainly women) with 20 μg vitamin D per day seemed to slightly reduce
all-cause mortality. The discrepancy between observational and intervention studies
suggests that low 25(OH)D is a marker of ill health. Inflammatory processes involved
in disease occurrence and clinical course would reduce 25(OH)D, which would explain
why low vitamin D status is reported in a wide range of disorders. In elderly people,
restoration of vitamin D deficits due to ageing and lifestyle changes induced by ill
health could explain why low-dose supplementation leads to slight gains in survival.
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