Saturday, June 6, 2020

Association between cholesterol levels and infections after ischemic stroke

Fascinating because the first thing your doctor is probably going to do is vastly reduce your cholesterol levels via drugs.

Association between cholesterol levels and infections after ischemic stroke

Mazzacane F, Leuci E, Persico A, et al
European Journal of Neurology|May 29, 2020
This single center prospective cohort study was undertaken to determine if cholesterol levels are correlated with the risk of infectious complications (IC) in patients with acute ischemic stroke. Total (TOTc), Low Density Lipoprotein and High Density Lipoprotein cholesterol levels have been measured within 24 hours from admission. The occurrence of any IC (pneumonia, urinary tract infection, sepsis, other infection) during hospitalization was the outcome of interest. There were a total of 603 patients (median age 78, 49.3% males), of whom 134 (22.2%) developed an IC. Patients with IC had lower TOTc vs patients without IC. In patients with ischemic stroke, higher cholesterol levels are independently linked to lower risk of IC. Further studies are needed to validate the results and to describe the underlying biological mechanisms of this association.
Read the full article on European Journal of Neurology.

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