Tuesday, June 9, 2020

Association Between Recent Cannabinoid Use and Acute Ischemic Stroke

Finally, we can get past the studies that correlated psychosis of psychotic patients using marijuana to that marijuana causing psychosis. 

Good, it also blew this research out of the water, probably because it looked at recent use. Hell, 40 years ago I smoked marijuana and that use would have caused my stroke? NO!

Study shows higher rate of stroke among pot smokers October 2018

 

My 13 reasons for marijuana use post-stroke.  

Don't follow me, I'm not medically trained and I don't have a Dr. in front of my name.

Just maybe you want this to occur:

Cannabis assists the endocannabinoid system in supporting the process of neurogenesis.

The latest here:

Association Between Recent Cannabinoid Use and Acute Ischemic Stroke

Carmela V. San Luis, Christa O’Hana S. Nobleza, Shashank Shekhar, Rebecca Sugg, Darren J. Villareal, Tapan Mehta, Shreyas Gangadhara
First published June 3, 2020, DOI: https://doi.org/10.1212/CPJ.0000000000000888
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ABSTRACT

Objective: 
Studies that have analyzed the association between cannabis use and acute ischemic stroke have provided conflicting results. In this study, we aim to determine the association of recent cannabis use detected through urine drug screen among patients admitted with acute ischemic stroke.
Methods: 
A retrospective observational study was performed utilizing the medical records database. All patients 18 years and older admitted from January 1, 2015 to December 31, 2017 who underwent urine toxicology testing on admission were included in the analysis. Multivariate logistic regression analysis was done to analyze independent association between recent cannabis use and acute ischemic stroke.
Results: 
A total of 9,350 patients were determined to have undergone urine drug screen during admission and 18% (1,643) of this had a positive urine cannabis test. Unadjusted risk ratio showed a 50% decrease in risk of acute ischemic stroke among cannabis users (RR = 0.505, 95% CI 0.425 – 0.600). The effect was lost after adjusting for age, race, ethnicity, sickle cell disease, dyslipidemia, hypertension, obesity, diabetes mellitus, cigarette smoking, atrial fibrillation, and other cardiac conditions (OR 1.038, 95% CI 0.773-1.394).
Conclusion: 
 This is one of the few studies analyzing the association of recent cannabis use and acute ischemic stroke using admission urine toxicology test independent of polysubstance use. Even though our study has limitations, we did not find an independent association between recent cannabis use and the incidence of acute ischemic stroke. Further studies utilizing urine toxicology tests with larger sample size and including dosage of cannabis exposure should be done.
  • Accepted April 7, 2020.

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