Saturday, June 27, 2020

Efficacy and safety of recanalization therapy for acute ischemic stroke with large vessel occlusion: A systematic review

Useless research, they don't tell us the definition of effective.  I'm sure it is not 100% recovery. 

Efficacy and safety of recanalization therapy for acute ischemic stroke with large vessel occlusion: A systematic review

Hui W, Wu C, Zha W, et al Stroke|June 23, 2020 A systematic review was conducted to analyze the efficacy and safety of recanalization therapy for acute ischemic stroke with large vessel occlusion. Researchers carried out to search PubMed, Embase, the Cochrane Central Register of Controlled Trials, and SinoMed, and a search was performed for clinical trials on ClinicalTrials.gov, the World Health Organization International Clinical Trials Registry Platform, and StrokeCenter.org. The study selection, data abstraction, and quality assessments were conducted by four independent reviewers. This study enrolled 17 trials including a total of 3,236 in and 8 ongoing clinical trials. The results showed that IVT+MT appears to be the most effective strategy, without increasing detrimental effects, for thrombolysis-eligible patients with large vessel occlusion acute ischemic stroke in comparison with other recanalization treatments. Future trials and real-world studies are warranted and should use unified definitions of symptomatic intracranial hemorrhage and recanalization to improve the current evidentiary basis for recanalization treatment. Read the full article on Stroke.

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