The Emerging Role of microRNAs in Post-ischemic Angiogenesis and Neurogenesis

A chapter in a new book; 'IschemiRs: MicroRNAs in Ischemic Stroke', $159.99

If your doctor did nothing with all this earlier research what the hell makes you think a book will be read on this and create protocols?

• microRNA (10)

• MicroRNA Let-7i (1)

• microRNA-124a (1)

• microRNA-129–5p (1)

• microRNA-141-3p (1)

• microRNA-210 (1)

• microRNA-223 (1)

• microRNA-9 (1)

The Emerging Role of microRNAs in Post-ischemic Angiogenesis and Neurogenesis

• Authors
• Authors and affiliations

• Rajanikant G. K.
• Pierre Gressens
• Sreekala S. Nampoothiri
• Gokul Surendran
• Cindy Bokobza

• Rajanikant G. K.
  • 1
  Email author
• Pierre Gressens
  • 2
• Sreekala S. Nampoothiri
  • 3
• Gokul Surendran
  • 1
• Cindy Bokobza
  • 2

1. 1.School of BiotechnologyNational Institute of Technology CalicutCalicutIndia
2. 2.NeuroDiderot, InsermUniversité de ParisParisFrance
3. 3.Development and Plasticity of the Neuroendocrine BrainLille Neuroscience & Cognition INSERM 1172LilleFrance

Chapter

First Online: 03 June 2020

• 5 Downloads

Abstract

Post-stroke angiogenic and neurogenic processes have become one of the highly studied domains to identify multifaceted therapeutic strategies bridging neurodevelopment and neuropathology. microRNAs (miRNAs) regulate the generation of new neurons in the stroke-damaged adult brain to propagate post-ischemic self-repair.(Sounds useful)

Similarly, a large number of individual miRNAs control endothelial cell (EC) proliferation and migration and promote vascular-network formation pertinent to angiogenesis. The expression of these miRNAs can be modulated to achieve structural and functional re-establishment of neurovascular networks after ischemic stroke. This chapter highlights the role of multiple miRNAs in different stages of post-ischemic neurogenesis and angiogenesis that potentially favor long-term recovery against ischemic stroke.