Emerging Neurology of COVID-19

You don't want these so don't stay home to tough it out.

I'm seeing a doctor as soon as I get symptoms and demanding heparin.Don't tough it out at home.

 Heparin binds to cells at a site adjacent to ACE2, the portal for SARS-CoV-2 infection, and "potently" blocks the virus, which could open up therapy options.

The latest here:

Emerging Neurology of COVID-19

Sana Somani MD, Shruti P. Agnihotri, MD

First Published July 10, 2020 Review Article 

https://doi.org/10.1177/1941874420936096

Article information

The virus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the current pandemic known as coronavirus disease 2019 (COVID-19) with severe respiratory illness as the predominant manifestation. Neurologic complications from COVID-19 were reported in the early stages of the pandemic and are now increasingly recognized. These include various symptoms like headache and anosmia as well as neurologic complications of severe COVID-19 like encephalopathy, seizures, and stroke. There are few reports of direct involvement of the central nervous system with SARS-CoV-2 causing meningoencephalitis. There is concern for higher incidence and severity of COVID-19 in patients with chronic neurologic conditions. Here, we review the emerging literature along with our anecdotal experience in regard to these neurologic manifestations in patients with COVID-19 and detail the putative pathophysiologic mechanisms for the same.

Keywords COVID-19, SARS-CoV-2, encephalopathy, meningoencephalitis

Introduction

An outbreak of a novel coronavirus disease starting in December 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has now taken over almost all countries of the world.¹ Infection with SARS-CoV-2, which has homologous sequences and pathogenesis similar to SARS-CoV-1, manifests primarily as respiratory illness.² However, various other systemic complications including that of gastrointestinal, renal, hematological, and rheumatological systems are increasingly recognized.³ Here, we review the neurologic issues related to COVID-19 based on the evolving literature and our experience (Table 1).

Table 1. Neurologic Issues Related

 Table is inserted below: